DIAMONDS FOR BIOSCIENCE 

Fluorescent Nanodiamonds (FNDs)

Cymaris fluorescent NV-center nanodiamonds (FNDs) are approximately 50 nm in size. They are typically excited at 532 nm and show steady, non-blinking emission centered at 700 nm. The diamonds are biocompatible, pH stable, non-quenching and are provided as stable colloidal suspensions.  Available with Polyethylene Glycol (PEG) of specific unit lengths (i.e. 4, 12, 36 PEG units) or proprietary surface coatings to increase conjugation and reduce non-specific binding.

 PEGYLATED FNDS 

NV FNDs available as Alcohol or Amine terminated, or  N-Hydroxysuccinimide (NHS) or MALeimide (MAL) derivatives . Custom functionalization available.



Alcohol-terminated PEG-FNDs 

Pricing & Details
Alcohol groups at the end of the PEG linker can be used for preparing custom conjugates of ultrabright and photostable fluorescently labeled biomolecules for labeling and tracking applications.

Amine-terminated PEG-FNDs
Pricing & Details
Amino PEG-FNDs react efficiently with isothiocyanates and succinimidyl esters, or with native carboxylic acids using water-soluble carbodiimides such as ethylene dichloride (EDC), and are the ideal starting material for preparing custom conjugates of ultrabright and photostable fluorescently labeled proteins or other biopolymers.

NHS-Activated PEG-FNDs
Pricing & Details
NHS is commonly used for labeling and crosslinking to the amines of other molecules.  Ideal for creating customized, fluorescently-labeled proteins, antibodies, and nucleic acids.   
Maleimide-Activated PEG-FNDs
Pricing & Details
Due to exceptionally fast reaction rates and significantly high selectivity towards cysteine residues in proteins, Maleimide-mediated methodologies are among the most used in bioconjugation.
* CUSTOM FUNCTIONALIZATION AVAILABLE ON REQUEST 






CONJUGATED NV FNDS

NV FNDs conjugated through PEG spacer with Streptavidin, Biotin or Antibodies.   Custom conjugations are available upon request. 



Streptavidin PEG-FNDs
Pricing & Details
Streptavidin probes are commonly used for specific detection of a variety of proteins, protein motifs, nucleic acids, and other molecules.  Useful in detection protocols including western blots, flow cytometry, imaging and microscopy, and microplate assays, and in purification workflows to achieve targeted fractionation.

Biotin PEG-FNDs 
Pricing & Details
Biotin-labeled NV FNDs are ideal for detecting streptavidin probes or for creating noncovalent conjugates with streptavidin-labeled molecules, or with other biotinylated molecules using a streptavidin bridge.

Antibody PEG-FNDs 
Pricing & Details
NV FNDs, conjugated to highly purified primary or secondary antibodies, are photo-stable, biocompatible probes for cell staining, targeted in vivo imaging, flow cytometry, western blotting, enzyme-linked Immunosorbent Assay (ELISA), and other applications that require extremely bright, non-toxic, targeted probes.

* CUSTOM CONJUGATIONS AVAILABLE ON REQUEST 





Non-PEGylated FNDS
NV FNDs with a proprietary coating.  Cymaris non-PEGylated FNDs provide a high degree of protection from non-specific binding, and provide surface functional alcohols or N-Hydroxysuccinimide (NHS) groups for preparing custom conjugations.



OH-FND
Pricing & Details


NHS-FNDs
Pricing & Details


* ADDITIONAL SURFACE FUNCTIONAL GROUPS AVAILABLE ON REQUEST